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February 02 2015

January 20 2015

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January 18 2015

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November 01 2014

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October 20 2014

Genomes reveal start of Ebola outbreak

Genomes reveal start of Ebola outbreak


When the young woman arrived at the Kenema Government Hospital in Sierra Leone in late May, she had high fever and had just miscarried. The hospital suspected she had contracted Lassa fever, because the viral disease is endemic in the region and often causes miscarriages. But Ebola virus disease, another hemorrhagic fever illness, had been spreading in neighboring Guinea for months, so when she began bleeding profusely, staff tested her for that virus as well. The results were positive, making her the first confirmed case of Ebola in Sierra Leone.

The young woman, who eventually recovered, is now at the heart of a tragic but potentially important research tale. In a paper online this week in Science, a collaboration led by Stephen Gire and Pardis Sabeti of Harvard University and the Broad Institute in Cambridge, Massachusetts, report sequencing and analyzing the genomes of Ebola virus samples from 78 people in Sierra Leone who were diagnosed with Ebola between late May and mid-June, including the young woman who came to Kenema’s hospital. The 99 complete sequences—some patients were sampled more than once—provide insights into how the virus is changing during the outbreak, which could help improve current diagnostic tests and, in the long term, guide researchers working on vaccines and treatments.


October 11 2014

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1 bedroom apartment floorplan

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September 21 2014

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June 30 2014

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figure 1: head drawings by Andrew Loomis, 1956

figure 2: women’s head designs can be generated by the same methods, they don’t have to all look very nearly the same

Some food for thought for drawing women and avoiding drawing a single female face.  Too often artists seem to be afraid to give women big noses or lines or other distinguishing features, and we end up with the same face on all the characters.  I’ve been browsing a lot of genderswap art lately and I’ve noticed that when male characters with large noses, thin faces, wrinkles, or other features get genderswapped, they tend to end up with small noses, round faces, and no wrinkles, and they no longer look distinct (they also look much younger than the original).  So, just some references and a reminder that women’s faces have all sorts of different features, and you don’t need to just have small cute features with no wrinkles to have a character look female.

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June 28 2014

June 17 2014

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Adventures of Tron & Tron: Deadly Discs, Atari 2600, Mattel Electronics, 1982.

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June 12 2014

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April 22 2014

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